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Synthetic Biologics, Inc. (NYSE MKT: SYN) is a clinical stage company developing therapeutics to protect the gut microbiome while targeting pathogen-specific diseases. The Company’s lead gut microbiome-focused programs poised for Phase 3 development include, SYN-010 a proprietary, modified-release formulation of lovastatin lactone intended to reduce the impact of methane producing organisms in the gut microbiome to treat an underlying cause of irritable bowel syndrome with constipation (IBS-C), and SYN-004 (ribaxamase), a first-in-class oral enzyme designed to protect the gut microbiome from the effects of certain commonly used intravenous (IV) beta-lactam antibiotics for the prevention of C. difficile infection, antibiotic-associated diarrhea (AAD) and the emergence of antibiotic resistant organisms. The Company is also developing preclinical stage monoclonal antibody therapies for the prevention and treatment of pertussis and novel discovery stage biotherapeutics for the treatment of phenylketonuria (PKU). For more information, please visit Synthetic Biologics’ website at www.syntheticbiologics.com.

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DNA Genotek provides high-quality biological sample collection, stabilization and preparation products for human genetics, microbiology and infectious disease applications. The company’s products protect and stabilize multiple sample types for long-term storage at ambient temperature to ensure the highest quality results for genetic analysis and testing. OMNIgene•GUT, DNA Genotek’s self-collection and stabilization kit for microbial DNA from feces, is the first and only device proven to immediately stabilize the microbiota profile at the moment of collection such that the in vivo state is accurately represented in the data analysis.  Microbial overgrowth and nucleic acid degradation are prevented during shipping, even at elevated temperatures, eliminating the cost and complexity of cold-chain shipping.  The expense of manual processing is also eliminated, as standardized liquid samples can be handled by robots.  This easy-to-use kit enables safe and reliable collection anywhere, anytime. Due to their reliability and ease-of-use, DNA Genotek’s products are used by thousands of academic, biotechnology, diagnostic, agriculture, and other leading institutions around the globe. DNA Genotek also offers GenoFIND™, a complete suite of genomics and microbiome services designed to combine our passion for customer service with industry leading sample collection and stabilization expertise.

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List Biological Laboratories, Inc. produces highly purified bacterial products for research as well as custom laboratory services. Scientists at pharmaceutical and biotech companies, universities, and government agencies can choose from over 100 products to aid in their studies. It all began in 1978 when Dr. Linda Shoer developed Cholera Toxin for research use. Over decades of working with bacteria and toxins, our expertise has expanded. Recently, we have gained experience producing bacterial which normally inhabit the human body; bacteria which may be used as live biotherapeutics.

We work with small start ups, large pharmaceutical and private companies interested in understanding and advancing the study of the human biome. Microbes living inside and outside humans outnumber human cells 10 to 1 and potentially affect everything from appetite to immunity. Such a complex network of microbes presents several research challenges. Many inhabitants of the human gut are strict anaerobes which must be handled using special practices and equipment.

Whether you need one of our standard toxins, a special protein, an LPS or custom batch of bacteria and if you are in early stages or more advanced in developing a product for the clinic, List Labs just might be the partner for you.